

| Catalog No. | HC380024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KRT17 Polyclonal Antibody (HC380024) is a rabbit polyclonal antibody detecting KRT17. Suitable for Rat, Human, and Mouse.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human KRT17 (Ala81-Arg432). | ||||||||
| Target | 39.1, CK-17, Cytokeratin-17, K17, KRT17, Keratin, type I cytoskeletal 17, Keratin-17 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q04695 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Keratin, type I cytoskeletal 17 (KRT17) is a ~48 kDa protein. Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-KRT17 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate



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