Anti-KRT17 Polyclonal Antibody (HC380014)

Name: Anti-KRT17 Polyclonal Antibody
Brand: abinScience
SKU: HC380014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC380014

Description

Anti-KRT17 Polyclonal Antibody (HC380014) is a rabbit polyclonal antibody detecting KRT17 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, Pan troglodytes, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KRT17 (Ile252-Ala393).

Target

Keratin-17, CK-17, Cytokeratin-17, 39.1, Keratin, type I cytoskeletal 17, K17, KRT17

Purification

Purified by antigen affinity column.

Accession

Q04695

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Keratin, type I cytoskeletal 17 (KRT17) is a ~48 kDa protein. Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.

Note

For research use only.

Images

References

Datasheet