Anti-Human LCAT Recombinant Antibody (SAA0536) (HY349013)

Name: Anti-Human LCAT Recombinant Antibody (SAA0536)
Brand: abinScience
SKU: HY349013
Price: 191 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY349013

Description

Anti-Human LCAT Recombinant Antibody (SAA0536) (HY349013) is a mouse monoclonal antibody detecting LCAT in Agonist, ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

Agonist, ELISA

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

SAA0536

Target

Platelet-activating factor acetylhydrolase, Phosphatidylcholine-sterol acyltransferase, Phospholipid-cholesterol acyltransferase, PAF acetylhydrolase, LCAT, 1-alkyl-2-acetylglycerophosphocholine esterase, Lecithin-cholesterol acyltransferase

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04180

RRID

Anti-Human LCAT Antibody (SAA0536) (abinScience Cat# HY349013, RRID:AB_3726061)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Phosphatidylcholine-sterol acyltransferase (LCAT) is a ~49 kDa protein. Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins.

1. Hirsch-Reinshagen, V. et al. (2009) Journal of lipid research 50, 885-93. PMID: 19065001

2. Subbaiah, PV. et al. (1996) Journal of lipid research 37, 113-22. PMID: 8820107

3. Forte, TM. et al. (1999) Journal of lipid research 40, 1276-83. PMID: 10393212

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human LCAT Antibody (SAA0536)

References

Datasheet

Anti-Human LCAT Recombinant Antibody (SAA0536).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LCAT Recombinant Antibody (SAA0536) (HY349013)

Overview

Images

References

Datasheet

SDS