Anti-Human LTBP1 Recombinant Antibody (SAA1797) (HC410013)

Name: Anti-Human LTBP1 Recombinant Antibody (SAA1797)
Brand: abinScience
SKU: HC410013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC410013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1797

Clonality

Monoclonal

Target

Transforming growth factor beta-1-binding protein 1, Latent-transforming growth factor beta-binding protein 1, LTBP-1, LTBP1, TGF-beta1-BP-1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14766

RRID

Anti-Human LTBP1 Antibody (SAA1797) (abinScience Cat# HC410013, RRID:AB_3727559)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Latent-transforming growth factor beta-binding protein 1 (LTBP1) is a ~186 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.

1. Miyazono, K. et al. (1991) The EMBO journal 10, 1091-101. PMID: 2022183

2. Saharinen, J. et al. (1996) The EMBO journal 15, 245-53. PMID: 8617200

3. Gleizes, PE. et al. (1996) The Journal of biological chemistry 271, 29891-6. PMID: 8939931

4. Annes, JP. et al. (2004) The Journal of cell biology 165, 723-34. PMID: 15184403

5. Wang, R. et al. (2012) Molecular biology of the cell 23, 1129-39. PMID: 22278742

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human LTBP1 Antibody (SAA1797)

References

Datasheet

Anti-Human LTBP1 Recombinant Antibody (SAA1797).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LTBP1 Recombinant Antibody (SAA1797) (HC410013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us