Anti-Human MADCAM1 Recombinant Antibody (SAA0147) (HC589107)

Name: Anti-Human MADCAM1 Recombinant Antibody (SAA0147)
Brand: abinScience
SKU: HC589107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HC589107
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG2, kappa
Clone ID	SAA0147
Clonality	Monoclonal
Target	MAdCAM-1, hMAdCAM-1, MADCAM1, Mucosal addressin cell adhesion molecule 1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q13477
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Mucosal addressin cell adhesion molecule 1 (MADCAM1) is a ~40 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Note	For research use only.

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Formula

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Overview