Anti-Human MAGEA6 Recombinant Antibody (SAA1840) (HW297013)

Name: Anti-Human MAGEA6 Recombinant Antibody (SAA1840)
Brand: abinScience
SKU: HW297013
Price: 196 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW297013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1840

Clonality

Monoclonal

Target

MAGEA6, Cancer/testis antigen 1.6, MAGE6, MAGE3B antigen, MAGE-6 antigen, CT1.6, Melanoma-associated antigen 6

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P43360

RRID

Anti-Human MAGEA6 Antibody (SAA1840) (abinScience Cat# HW297013, RRID:AB_3727603)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Melanoma-associated antigen 6 (MAGEA6) is a ~34 kDa protein. Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

1. Yang, B. et al. (2007) Cancer research 67, 9954-62. PMID: 17942928

2. Doyle, JM. et al. (2010) Molecular cell 39, 963-74. PMID: 20864041

3. Ravichandran, R. et al. (2019) EMBO reports 20, e47352. PMID: 31267705

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MAGEA6 Antibody (SAA1840)

References

Datasheet

Anti-Human MAGEA6 Recombinant Antibody (SAA1840).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MAGEA6 Recombinant Antibody (SAA1840) (HW297013)

Overview

Images

References

Datasheet

SDS

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