Anti-Human MATR3 Polyclonal Antibody (HW326014)

Name: Anti-Human MATR3 Polyclonal Antibody
Brand: abinScience
SKU: HW326014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HW326014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MATR3 (Lys478-Val576).

Target

Matrin-3, KIAA0723, MATR3

Purification

Purified by antigen affinity column.

Accession

P43243

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Matrin-3 (MATR3) is a ~94 kDa protein. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins.

1. Morchikh, M. et al. (2017) Molecular cell 67, 387-399.e5. PMID: 28712728

2. Zhu, S. et al. (2020) Nature communications 11, 1685. PMID: 32245947

3. Treiber, T. et al. (2017) Molecular cell 66, 270-284.e13. PMID: 28431233

Note

For research use only.

Images

References

Datasheet

Anti-Human MATR3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human MATR3 Polyclonal Antibody (HW326014)

Overview

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References

Datasheet

SDS

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