Human MATR3 Recombinant Protein (N-GST & C-His) (HW326022)

Name: Human MATR3 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HW326022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW326022
Description	Recombinant Human MATR3 Protein, N-GST & C-His (HW326022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P43243
Protein length	Lys478-Val576
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KIAA0723, MATR3, Matrin-3
Background	Matrin-3 is a ~94 kDa protein. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins. 1. Morchikh, M. et al. (2017) Molecular cell 67, 387-399.e5. PMID: 28712728 2. Zhu, S. et al. (2020) Nature communications 11, 1685. PMID: 32245947 3. Treiber, T. et al. (2017) Molecular cell 66, 270-284.e13. PMID: 28431233
Note	For research use only

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Datasheet

Human MATR3 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Human MATR3 Recombinant Protein (N-GST & C-His) (HW326022)

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