Anti-Human MCIDAS Polyclonal Antibody (HA153014)

Name: Anti-Human MCIDAS Polyclonal Antibody
Brand: abinScience
SKU: HA153014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HA153014

Description

Anti-Human MCIDAS Polyclonal Antibody (HA153014) is a rabbit polyclonal antibody detecting McIdas protein in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MCIDAS (Thr314-Ser385).

Target

Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN

Purification

Purified by antigen affinity column.

Accession

D6RGH6

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Multicilin (MCIDAS) is a ~41 kDa protein. Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.

1. Boon, M. et al. (2014) Nature communications 5, 4418. PMID: 25048963

2. Pefani, DE. et al. (2011) The Journal of biological chemistry 286, 23234-46. PMID: 21543332

3. Caillat, C. et al. (2013) The Journal of biological chemistry 288, 31624-34. PMID: 24064211

Note

For research use only.

Images

References

Datasheet

Anti-Human MCIDAS Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MCIDAS Polyclonal Antibody (HA153014)

Overview

Images

References

Datasheet

SDS

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