Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

Name: Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12)
Brand: abinScience
SKU: HV344043
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV344043

Species reactivity

Human, Mouse

Applications

ELISA, Neutralization

Host species

Mouse

Isotype

IgG2a-kappa

Clone ID

14D12

Clonality

Monoclonal

Target

ANGPTL4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9BY76

RRID

Anti-Human/Mouse ANGPTL4 Antibody (14D12) (abinScience Cat# HV344043, RRID:AB_3729819)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternate Names

Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP, ANGPTL4 N-terminal chain, ANGPTL4 C-terminal chain, ANGPTL4

Background

Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis.

1. Yin, W. et al. (2009) The Journal of biological chemistry 284, 13213-22. PMID: 19270337

2. Lei, X. et al. (2011) The Journal of biological chemistry 286, 15747-56. PMID: 21398697

3. Mysling, S. et al. (2016) eLife 5. PMID: 27929370

4. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144

5. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458

6. Cazes, A. et al. (2006) Circulation research 99, 1207-15. PMID: 17068295

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human/Mouse ANGPTL4 Antibody (14D12)

References

Datasheet

Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human/Mouse ANGPTL4 Recombinant Antibody (14D12) (HV344043)

Overview

Images

References

Datasheet

SDS

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