Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934) (HF729013)

Name: Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934)
Brand: abinScience
SKU: HF729013
Price: 110 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF729013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1934

Clonality

Monoclonal

Target

G6B, G6B-B, Protein G6b, MPIG6B, C6orf25, Megakaryocyte and platelet inhibitory receptor G6b

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95866

RRID

Anti-Human MPIG6B/G6b Antibody (SAA1934) (abinScience Cat# HF729013, RRID:AB_3727698)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Megakaryocyte and platelet inhibitory receptor G6b (MPIG6B) is a ~26 kDa protein. Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner.

1. Gevaert, K. et al. (2003) Nature biotechnology 21, 566-9. PMID: 12665801

2. Newland, SA. et al. (2007) Blood 109, 4806-9. PMID: 17311996

3. Melhem, M. et al. (2017) European journal of haematology 98, 218-227. PMID: 27743390

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MPIG6B/G6b Antibody (SAA1934)

References

Datasheet

Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MPIG6B/G6b Recombinant Antibody (SAA1934) (HF729013)

Overview

Images

References

Datasheet

SDS

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