Anti-Human NAP1L1 Polyclonal Antibody (HX949014)

Name: Anti-Human NAP1L1 Polyclonal Antibody
Brand: abinScience
SKU: HX949014
Price: 96 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HX949014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NAP1L1 (Arg72-Glu356).

Target

NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1

Purification

Purified by antigen affinity column.

Accession

P55209

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Nucleosome assembly protein 1-like 1 (NAP1L1) is a ~45 kDa protein. Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development.

1. Okuwaki, M. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 13-27. PMID: 20002496

2. Mehrotra, PV. et al. (2011) Molecular cell 41, 46-55. PMID: 21211722

3. Ohtomo, H. et al. (2016) Genes to cells : devoted to molecular & cellular mechanisms 21, 252-63. PMID: 26841755

4. Lee, JY. et al. (2017) Nucleic acids research 45, 4696-4707. PMID: 28369616

5. Machida, S. et al. (2014) Scientific reports 4, 4863. PMID: 24798879

Note

For research use only.

Images

References

Datasheet

Anti-Human NAP1L1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human NAP1L1 Polyclonal Antibody (HX949014)

Overview

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References

Datasheet

SDS

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