Anti-Human PAPPA Monoclonal Antibody (1A407) (HC474025)

Name: Anti-Human PAPPA Monoclonal Antibody (1A407)
Brand: abinScience
SKU: HC474025
Price: 194 USD
Availability: InStock

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Overview

Catalog No.	HC474025
Description	Anti-Human PAPPA Monoclonal Antibody (1A407) [1A407] (HC474025) is a mouse monoclonal antibody detecting PAPPA in ELISA. Suitable for Human.
Species reactivity	Human
Applications	ELISA
Host species	Mouse
Isotype	IgG
Clone ID	1A407
Clonality	Monoclonal
Immunogen	Human PAPPA Protein.
Target	Pappalysin-1, 3.4.24.79, Insulin-like growth factor-dependent IGF-binding protein 4 protease, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Pregnancy-associated plasma protein A, PAPP-A, PAPPA
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q13219
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Pappalysin-1 is a ~180 kDa protein. Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Note	For research use only.

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Overview