Anti-Human PAPPA Polyclonal Antibody (HC474014)

Name: Anti-Human PAPPA Polyclonal Antibody
Brand: abinScience
SKU: HC474014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC474014

Description

Anti-Human PAPPA Polyclonal Antibody (HC474014) is a rabbit polyclonal antibody detecting PAPPA. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PAPPA (Leu317-Pro532).

Target

EC:3.4.24.79, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Insulin-like growth factor-dependent IGF-binding protein 4 protease, PAPP-A, PAPPA, Pappalysin-1, Pregnancy-associated plasma protein A

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q13219

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Pappalysin-1 is a ~180 kDa protein. Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.

Note

For research use only

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References

Datasheet