Anti-Human POLG2 Polyclonal Antibody (HD645014)

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HD645014

Description

Anti-Human POLG2 Polyclonal Antibody (HD645014) is a rabbit polyclonal antibody detecting POLG2. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human POLG2 (Arg182-Val485).

Target

DNA polymerase gamma accessory 55 kDa subunit, DNA polymerase subunit gamma-2, MTPOLB, Mitochondrial DNA polymerase accessory subunit, MtPolB, POLG2, PolG-beta, p55

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q9UHN1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

DNA polymerase subunit gamma-2 (POLG2) is a ~54 kDa protein. Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA.

Note

For research use only

Images

References

Datasheet

Anti-Human POLG2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human POLG2 Polyclonal Antibody (HD645014)

Overview

Images

References

Datasheet

SDS

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