Anti-Human PTH Monoclonal Antibody (1A677) (HF921015)

Name: Anti-Human PTH Monoclonal Antibody (1A677)
Brand: abinScience
SKU: HF921015
Price: 194 USD
Availability: InStock

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Overview

Catalog No.	HF921015
Description	Anti-Human PTH Monoclonal Antibody (1A677) [1A677] (HF921015) is a mouse monoclonal antibody detecting PTH in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A677
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human PTH (Ser32-Gln115).
Target	Parathyroid hormone, PTH, Parathormone, Parathyrin, PTH
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01270
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Parathyroid hormone (PTH) is a ~12 kDa protein. Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. 1. Shimizu, N. et al. (2001) The Journal of biological chemistry 276, 49003-12. PMID: 11604398 2. Kobayashi, K. et al. (2022) Molecular cell 82, 3468-3483.e5. PMID: 35932760 3. Pioszak, AA. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5034-9. PMID: 18375760 4. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856
Note	For research use only.