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Anti-Human PYDC2 Polyclonal Antibody (HD282014)

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Overview
Catalog No.HD282014
Description
Anti-Human PYDC2 Polyclonal Antibody (HD282014) is a rabbit polyclonal antibody detecting PYDC2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human PYDC2 (Met1-Pro97).
Target POP2, PYDC2, Pyrin domain-containing protein 2, Pyrin-only protein 2, cPOP2, cellular POP2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q56P42
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Pyrin domain-containing protein 2 (PYDC2) is a ~10 kDa protein. May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome. May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA.

1. Dorfleutner, A. et al. (2007) Infection and immunity 75, 1484-92. PMID: 17178784
2. Bedoya, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 3837-45. PMID: 17339483
3. Porter, KA. et al. (2014) Genes and immunity 15, 392-403. PMID: 24871464
Note For research use only
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Formula
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Anti-Human PYDC2 Polyclonal Antibody

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