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Anti-Human RPS6KB2 Polyclonal Antibody (HV593014)

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Overview
Catalog No.HV593014
Description
Anti-Human RPS6KB2 Polyclonal Antibody (HV593014) is a rabbit polyclonal antibody detecting RPS6KB2. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human RPS6KB2 (Arg61-Ser403).
Target 70 kDa ribosomal protein S6 kinase 2, EC:2.7.11.1, P70S6K2, RPS6KB2, Ribosomal protein S6 kinase beta-2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, S6K2, SRK, STK14B, Serine/threonine-protein kinase 14B, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70 ribosomal S6 kinase beta, p70-S6K 2, p70-beta
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9UBS0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Ribosomal protein S6 kinase beta-2 (RPS6KB2) is a ~53 kDa protein. Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.

1. Nguyen, JT. et al. (2018) Science advances 4, eaao5838. PMID: 29750193
Note For research use only
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Formula
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human RPS6KB2 Polyclonal Antibody

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