

| Catalog No. | HV593022 |
|---|---|
| Description |
Recombinant Human RPS6KB2 Protein, N-His (HV593022) expressed in E. coli, spanning Arg61-Ser403. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q9UBS0 |
| Protein length | Arg61-Ser403 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 40.88 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 70 kDa ribosomal protein S6 kinase 2, EC:2.7.11.1, P70S6K2, RPS6KB2, Ribosomal protein S6 kinase beta-2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, S6K2, SRK, STK14B, Serine/threonine-protein kinase 14B, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70 ribosomal S6 kinase beta, p70-S6K 2, p70-beta |
| Background | Ribosomal protein S6 kinase beta-2 is a ~53 kDa protein. Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. 1. Nguyen, JT. et al. (2018) Science advances 4, eaao5838. PMID: 29750193 |
| Note | For research use only |
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