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Human RPS6KB2 Recombinant Protein (N-His) (HV593022)

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Overview
Catalog No.HV593022
Description
Recombinant Human RPS6KB2 Protein, N-His (HV593022) expressed in E. coli, spanning Arg61-Ser403. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ9UBS0
Protein lengthArg61-Ser403
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 40.88 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names70 kDa ribosomal protein S6 kinase 2, EC:2.7.11.1, P70S6K2, RPS6KB2, Ribosomal protein S6 kinase beta-2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, S6K2, SRK, STK14B, Serine/threonine-protein kinase 14B, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70 ribosomal S6 kinase beta, p70-S6K 2, p70-beta
Background

Ribosomal protein S6 kinase beta-2 is a ~53 kDa protein. Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.

1. Nguyen, JT. et al. (2018) Science advances 4, eaao5838. PMID: 29750193
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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