

| Catalog No. | HY242013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1556 | ||||
| Clonality | Monoclonal | ||||
| Target | S100 calcium-binding protein A8, Urinary stone protein band A, MRP8, Cystic fibrosis antigen, Calprotectin L1L subunit, MRP-8, p8, Calgranulin-A, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, S100A8, Protein S100-A8, CAGA, CFAG | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P05109 | ||||
| RRID | Anti-Human S100A8 Antibody (SAA1556) (abinScience Cat# HY242013, RRID:AB_3727317) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Protein S100-A8 (S100A8) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. 1. Lin, CR. et al. (2015) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 29, 5006-17. PMID: 26296369 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human S100A8 Antibody (SAA1556)



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