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Anti-Human S100A8 Polyclonal Antibody (HY242024)

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Overview
Catalog No.HY242024
Description
Anti-Human S100A8 Polyclonal Antibody (HY242024) is a rabbit polyclonal antibody detecting S100A8. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human S100A8 (Met1-Glu93).
Target CAGA, CFAG, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MRP-8, MRP8, Migration inhibitory factor-related protein 8, Protein S100-A8, S100 calcium-binding protein A8, S100A8, Urinary stone protein band A, p8
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P05109
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Protein S100-A8 (S100A8) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69.

1. Lin, CR. et al. (2015) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 29, 5006-17. PMID: 26296369
Note For research use only
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Formula
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Anti-Human S100A8 Polyclonal Antibody

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