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Anti-Human SLC15A1 Polyclonal Antibody (HA507014)

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Overview
Catalog No.HA507014
Description
Anti-Human SLC15A1 Polyclonal Antibody (HA507014) is a rabbit polyclonal antibody detecting SLC15A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human SLC15A1 (Asp383-Gln584).
Target SLC15A1
Purification Purified by antigen affinity column.
Accession P46059
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesSolute carrier family 15 member 1, Intestinal H(+)/peptide cotransporter, Oligopeptide transporter, small intestine isoform, Peptide transporter 1, SLC15A1, PEPT1
Background

Solute carrier family 15 member 1 (SLC15A1) is a ~78 kDa protein. Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen. Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system.

1. Vavricka, SR. et al. (2004) Gastroenterology 127, 1401-9. PMID: 15521010
2. Sala-Rabanal, M. et al. (2008) American journal of physiology. Renal physiology 294, F1422-32. PMID: 18367661
3. Xu, L. et al. (2009) Pharmaceutical research 26, 2358-66. PMID: 19685173
4. Beale, JH. et al. (2015) Structure (London, England : 1993) 23, 1889-1899. PMID: 26320580
5. Liang, R. et al. (1995) The Journal of biological chemistry 270, 6456-63. PMID: 7896779
6. Mackenzie, B. et al. (1996) Biochimica et biophysica acta 1284, 125-8. PMID: 8914574
7. Merlin, D. et al. (1998) The Journal of clinical investigation 102, 2011-8. PMID: 9835627
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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