Anti-Human SLC22A5 Polyclonal Antibody (HF955014)

Name: Anti-Human SLC22A5 Polyclonal Antibody
Brand: abinScience
SKU: HF955014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HF955014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC22A5 (Thr45-Lys141).

Target

SLC22A5, Organic cation/carnitine transporter 2, High-affinity sodium-dependent carnitine cotransporter, OCTN2, Solute carrier family 22 member 5

Purification

Purified by antigen affinity column.

Accession

O76082

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Organic cation/carnitine transporter 2 (SLC22A5) is a ~62 kDa protein. Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 11.3.

1. Wu, X. et al. (1999) The Journal of pharmacology and experimental therapeutics 290, 1482-92. PMID: 10454528

2. Ohashi, R. et al. (1999) The Journal of pharmacology and experimental therapeutics 291, 778-84. PMID: 10525100

3. Wagner, CA. et al. (2000) American journal of physiology. Renal physiology 279, F584-91. PMID: 10966938

4. Maekawa, S. et al. (2007) Biochimica et biophysica acta 1773, 1000-6. PMID: 17509700

5. Fujiya, M. et al. (2011) Inflammatory bowel diseases 17, 907-16. PMID: 20722056

6. Yee, SW. et al. (2020) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 15734-15752. PMID: 33124720

7. Fujiya, M. et al. (2007) Cell host & microbe 1, 299-308. PMID: 18005709

Note

For research use only.

Images

References

Datasheet

Anti-Human SLC22A5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC22A5 Polyclonal Antibody (HF955014)

Overview

Images

References

Datasheet

SDS

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