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Anti-Human SLC25A1 Polyclonal Antibody (HC027014)

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Overview
Catalog No.HC027014
Description
Anti-Human SLC25A1 Polyclonal Antibody (HC027014) is a rabbit polyclonal antibody detecting mitochondrial; Citrate transport protein; CTP; Mitochondrial citrate carrier; CIC; Solute carrier family 25 member 1; Tricarboxylate carrier protein; SLC25A1; SLC20A3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant human SLC25A1 (Glu47-Arg85&Glu106-Gly128&Glu144-Gln182&Leu241-Gly278).
Target Tricarboxylate transport protein, mitochondrial; Citrate transport protein; CTP; Mitochondrial citrate carrier; CIC; Solute carrier family 25 member 1; Tricarboxylate carrier protein; SLC25A1; SLC20A3
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P53007
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tricarboxylate transport protein, mitochondrial (SLC25A1) is a ~34 kDa protein. Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extent trans-aconitate, maleate and succinate. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. In the cytoplasm, citrate plays important roles in fatty acid and sterol synthesis, regulation of glycolysis, protein acetylation, and other physiopathological processes.

1. Chaouch, A. et al. (2014) Journal of neuromuscular diseases 1, 75-90. PMID: 26870663
2. Majd, H. et al. (2018) Biochimica et biophysica acta. Bioenergetics 1859, 1-7. PMID: 29031613
3. Pop, A. et al. (2018) Journal of inherited metabolic disease 41, 169-180. PMID: 29238895
4. Li, W. et al. (2025) The EMBO journal 44, 1641-1662. PMID: 39881208
5. Cimadamore-Werthein, C. et al. (2024) The EMBO journal 43, 3450-3465. PMID: 38937634
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human SLC25A1 Polyclonal Antibody

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