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Anti-Human SMYD3 Polyclonal Antibody (HP320024)

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Overview
Catalog No.HP320024
Description
Anti-Human SMYD3 Polyclonal Antibody (HP320024) is a rabbit polyclonal antibody detecting SMYD3. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SMYD3 (Met1-Ser428).
Target EC:2.1.1.354, Histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, SMYD3, ZMYND1, ZNFN3A1, Zinc finger MYND domain-containing protein 1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9H7B4
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Histone-lysine N-methyltransferase SMYD3 is a ~49 kDa protein. Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys-5' of histone H4. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.

1. Hamamoto, R. et al. (2004) Nature cell biology 6, 731-40. PMID: 15235609
2. Van Aller, GS. et al. (2012) Epigenetics 7, 340-3. PMID: 22419068
Note For research use only
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Formula
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human SMYD3 Polyclonal Antibody

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