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Anti-Human SSB Polyclonal Antibody (HY125014)

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Overview
Catalog No.HY125014
Description
Anti-Human SSB Polyclonal Antibody (HY125014) is a rabbit polyclonal antibody detecting SSB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SSB (Ala2-Lys185).
Target La autoantigen, La ribonucleoprotein, Lupus La protein, SS-B, SSB, Sjoegren syndrome type B antigen
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P05455
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Lupus La protein (SSB) is a ~46 kDa protein. Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.

1. Gottlieb, E. et al. (1989) The EMBO journal 8, 851-61. PMID: 2470590
2. Chambers, JC. et al. (1988) The Journal of biological chemistry 263, 18043-51. PMID: 3192525
3. Ray, PS. et al. (2002) Nucleic acids research 30, 4500-8. PMID: 12384597
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human SSB Polyclonal Antibody

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