

| Catalog No. | HY125032 |
|---|---|
| Description |
Recombinant Human SSB Protein, N-GST & C-His (HY125032) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P05455 |
| Protein length | Ala2-Lys185 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | La autoantigen, La ribonucleoprotein, Lupus La protein, SS-B, SSB, Sjoegren syndrome type B antigen |
| Background | Lupus La protein is a ~46 kDa protein. Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. 1. Gottlieb, E. et al. (1989) The EMBO journal 8, 851-61. PMID: 2470590 2. Chambers, JC. et al. (1988) The Journal of biological chemistry 263, 18043-51. PMID: 3192525 3. Ray, PS. et al. (2002) Nucleic acids research 30, 4500-8. PMID: 12384597 |
| Note | For research use only |



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