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Anti-Human STEAP4 Recombinant Antibody (SAA2400) (HP364023)

Anti-Human STEAP4 Recombinant Antibody (SAA2400)
Anti-Human STEAP4 Recombinant Antibody (SAA2400)
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Overview
Catalog No.HP364023
Species reactivityHuman
ApplicationsELISA, WB
Host speciesRabbit
IsotypeIgG
Clone IDSAA2400
Clonality Monoclonal
Target Metalloreductase STEAP4, EC:1.16.1.-, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9
Endotoxin level <10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q687X5
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
WB 1:500-1:2000
Background

Metalloreductase STEAP4 is a ~51 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance.

1. Oosterheert, W. et al. (2018) Nature communications 9, 4337. PMID: 30337524
2. Arner, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 2249-54. PMID: 18381574
3. Zhang, CM. et al. (2008) Acta pharmacologica Sinica 29, 587-92. PMID: 18430367
4. Inoue, A. et al. (2009) Arthritis research & therapy 11, R118. PMID: 19660107
5. Tamura, T. et al. (2009) International journal of molecular medicine 24, 599-604. PMID: 19787193
Note For research use only
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  • Anti-Human STEAP4 Recombinant Antibody (SAA2400)

    SDS-PAGE

    SDS-PAGE for Anti-Human STEAP4 Antibody (SAA2400)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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