

| Catalog No. | HP364023 | ||||||
|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||
| Applications | ELISA, WB | ||||||
| Host species | Rabbit | ||||||
| Isotype | IgG | ||||||
| Clone ID | SAA2400 | ||||||
| Clonality | Monoclonal | ||||||
| Target | Metalloreductase STEAP4, EC:1.16.1.-, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9 | ||||||
| Endotoxin level | <10 EU/mg | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | Q687X5 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Metalloreductase STEAP4 is a ~51 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. 1. Oosterheert, W. et al. (2018) Nature communications 9, 4337. PMID: 30337524 2. Arner, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 2249-54. PMID: 18381574 3. Zhang, CM. et al. (2008) Acta pharmacologica Sinica 29, 587-92. PMID: 18430367 4. Inoue, A. et al. (2009) Arthritis research & therapy 11, R118. PMID: 19660107 5. Tamura, T. et al. (2009) International journal of molecular medicine 24, 599-604. PMID: 19787193 | ||||||
| Note | For research use only |

SDS-PAGE for Anti-Human STEAP4 Antibody (SAA2400)



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