

| Catalog No. | HW729023 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SULT1E1 Recombinant Antibody (SAA0759) (HW729023) is a rabbit monoclonal antibody detecting SULT1E1 in ELISA, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||
| Applications | ELISA, WB | ||||||
| Host species | Rabbit | ||||||
| Clonality | Monoclonal | ||||||
| Isotype | IgG | ||||||
| Clone ID | SAA0759 | ||||||
| Target | ST1E1, STE, EST-1, SULT1E1, Sulfotransferase 1E1, Sulfotransferase, estrogen-preferring, Estrogen sulfotransferase | ||||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | P49888 | ||||||
| RRID | Anti-Human SULT1E1 Antibody (SAA0759) (abinScience Cat# HW729023, RRID:AB_3726305) |
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| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Background | Sulfotransferase 1E1 (SULT1E1) is a ~35 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine. May play a role in gut microbiota-host metabolic interaction. 1. Hempel, N. et al. (2000) Biochemical and biophysical research communications 276, 224-30. PMID: 11006110 2. Pedersen, LC. et al. (2002) The Journal of biological chemistry 277, 17928-32. PMID: 11884392 3. Falany, CN. et al. (1995) The Journal of steroid biochemistry and molecular biology 52, 529-39. PMID: 7779757 4. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human SULT1E1 Antibody (SAA0759)




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