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Anti-Human TP53INP1 Polyclonal Antibody (HP996014)

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Overview
Catalog No.HP996014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human TP53INP1 (Gln86-Ser130).
Target Stress-induced protein, P53DINP1, TP53INP1, Tumor protein p53-inducible nuclear protein 1, p53DINP1, SIP, p53-dependent damage-inducible nuclear protein 1
Purification Purified by antigen affinity column.
Accession Q96A56
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tumor protein p53-inducible nuclear protein 1 (TP53INP1) is a ~27 kDa protein. Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function.

Note For research use only.
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Formula
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Anti-Human TP53INP1 Polyclonal Antibody

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