Human TP53INP1 Recombinant Protein (N-GST & C-His) (HP996022)

Name: Human TP53INP1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP996022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP996022
Description	Recombinant Human TP53INP1 Protein, N-GST & C-His (HP996022) expressed in E. coli, spanning Gln86-Ser130. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q96A56
Protein length	Gln86-Ser130
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	33.20 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	P53DINP1, SIP, Stress-induced protein, TP53INP1, Tumor protein p53-inducible nuclear protein 1, p53-dependent damage-inducible nuclear protein 1, p53DINP1
Background	Tumor protein p53-inducible nuclear protein 1 is a ~27 kDa protein. Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function.
Note	For research use only

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Datasheet

Human TP53INP1 Recombinant Protein (N-GST & C-His).pdf

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Human TP53INP1 Recombinant Protein (N-GST & C-His) (HP996022)

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