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Anti-Human UBE2G2 Polyclonal Antibody (HD110014)

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Overview
Catalog No.HD110014
Description
Anti-Human UBE2G2 Polyclonal Antibody (HD110014) is a rabbit polyclonal antibody detecting UBE2G2. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human UBE2G2 (Met1-Leu165).
Target E2 ubiquitin-conjugating enzyme G2, EC:2.3.2.23, UBC7, UBE2G2, Ubiquitin carrier protein G2, Ubiquitin-conjugating enzyme E2 G2, Ubiquitin-protein ligase G2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P60604
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) is a ~18 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation.

1. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386
2. Sato, T. et al. (2012) Molecular cell 47, 99-110. PMID: 22607976
3. Jo, Y. et al. (2013) Molecular biology of the cell 24, 169-83. PMID: 23223569
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human UBE2G2 Polyclonal Antibody

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