Anti-Human UCP3 Polyclonal Antibody (HX158014)

Name: Anti-Human UCP3 Polyclonal Antibody
Brand: abinScience
SKU: HX158014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX158014

Description

Anti-Human UCP3 Polyclonal Antibody (HX158014) is a rabbit polyclonal antibody detecting UCP3 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UCP3 (Met1-Phe312).

Target

UCP3

Purification

Purified by antigen affinity column.

Accession

P55916

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, UCP3, SLC25A9

Background

Putative mitochondrial transporter UCP3 is a ~34 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.

1. De Marchi, U. et al. (2011) The Journal of biological chemistry 286, 32533-41. PMID: 21775425

2. Codella, R. et al. (2023) FEBS letters 597, 309-319. PMID: 36114012

3. Echtay, KS. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 1416-21. PMID: 11171965

4. Zackova, M. et al. (2003) The Journal of biological chemistry 278, 20761-9. PMID: 12670931

5. Jaburek, M. et al. (2003) The Journal of biological chemistry 278, 25825-31. PMID: 12734183

6. Gong, DW. et al. (1997) The Journal of biological chemistry 272, 24129-32. PMID: 9305858

7. Cadenas, S. et al. (2002) The Journal of biological chemistry 277, 2773-8. PMID: 11707458

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-UCP3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse heart lysate
Lane 3: Rat liver lysate
Lane 4: Rat heart lysate

References

Datasheet

Anti-Human UCP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human UCP3 Polyclonal Antibody (HX158014)

Overview

Images

References

Datasheet

SDS

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