Anti-Human UNC5B Antibody (SAA1865) (HA978013)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

HA978013

Description

Anti-Human UNC5B Antibody (SAA1865) [SAA1865] (HA978013) is a mouse monoclonal antibody detecting UNC5B in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1865

Clonality

Monoclonal

Target

Netrin receptor UNC5B, Protein unc-5 homolog B, Protein unc-5 homolog 2, P53RDL1, UNC5B, p53-regulated receptor for death and life protein 1, UNC5H2, p53RDL1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IZJ1

RRID

Anti-Human UNC5B Antibody (SAA1865) (abinScience Cat# HA978013, RRID:AB_3727628)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Netrin receptor UNC5B is a ~103 kDa protein. Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Functions as a netrin receptor that negatively regulates vascular branching during angiogenesis. Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin.

1. Tanikawa, C. et al. (2003) Nature cell biology 5, 216-23. PMID: 12598906

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human UNC5B Antibody (SAA1865)

References

Datasheet

Anti-Human UNC5B Antibody (SAA1865).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human UNC5B Antibody (SAA1865) (HA978013)

Overview

Images

References

Datasheet

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