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Anti-UNC5B Recombinant Antibody (YW88) (HA978023)

Anti-UNC5B Recombinant Antibody (YW88)
Anti-UNC5B Recombinant Antibody (YW88)
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Overview
Catalog No.HA978023
Species reactivityHuman
ApplicationsELISA, FACS, Functional assay
Host speciesHuman
IsotypeIgG1, kappa
Clone IDYW88
Clonality Monoclonal
Target Netrin receptor UNC5B, Protein unc-5 homolog 2, Protein unc-5 homolog B, p53-regulated receptor for death and life protein 1, p53RDL1, UNC5B, P53RDL1, UNC5H2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q8IZJ1
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Netrin receptor UNC5B is a ~103 kDa protein. Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Functions as a netrin receptor that negatively regulates vascular branching during angiogenesis. Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin.

1. Tanikawa, C. et al. (2003) Nature cell biology 5, 216-23. PMID: 12598906
Note For research use only
Images
  • Anti-UNC5B Recombinant Antibody (YW88)

    SDS-PAGE

    SDS-PAGE for Anti-UNC5B Antibody (YW88)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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