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Anti-Human UTP25 Polyclonal Antibody (HD313014)

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Overview
Catalog No.HD313014
Description
Anti-Human UTP25 Polyclonal Antibody (HD313014) is a rabbit polyclonal antibody detecting UTP25. Suitable for Rat, Mouse, and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human UTP25 (Asn180-Asn561).
Target C1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q68CQ4
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

U3 small nucleolar RNA-associated protein 25 homolog (UTP25) is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53.

1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851
2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945
3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329
Note For research use only
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Formula
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