

| Catalog No. | HD313014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human UTP25 Polyclonal Antibody (HD313014) is a rabbit polyclonal antibody detecting UTP25. Suitable for Rat, Mouse, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human UTP25 (Asn180-Asn561). | ||||||||
| Target | C1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q68CQ4 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | U3 small nucleolar RNA-associated protein 25 homolog (UTP25) is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53. 1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851 2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945 3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329 | ||||||||
| Note | For research use only |
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