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Human UTP25 Recombinant Protein (N-His) (HD313012)

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Overview
Catalog No.HD313012
Description
Recombinant Human UTP25 Protein, N-His (HD313012) expressed in E. coli, spanning Asn180-Asn561. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ68CQ4
Protein lengthAsn180-Asn561
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 46.33 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesC1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component
Background

U3 small nucleolar RNA-associated protein 25 homolog is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53.

1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851
2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945
3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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