Anti-ICK Recombinant Antibody (N451/29) (HV486023)

Name: Anti-ICK Recombinant Antibody (N451/29)
Brand: abinScience
SKU: HV486023
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV486023

Description

Anti-ICK Recombinant Antibody (N451/29) (HV486023) is a mouse monoclonal antibody detecting CILK1 in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N451/29

Target

Ciliogenesis associated kinase 1, Serine/threonine-protein kinase ICK, MAK-related kinase, ICK, KIAA0936, hICK, Laryngeal cancer kinase 2, CILK1, MRK, LCK2, Intestinal cell kinase

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-ICK Antibody (N451/29) (abinScience Cat# HV486023, RRID:AB_3728905)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Serine/threonine-protein kinase ICK (CILK1) is a ~71 kDa protein. Required for ciliogenesis. Phosphorylates KIF3A. Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips. May play a key role in the development of multiple organ systems and particularly in cardiac development.

1. Chaya, T. et al. (2014) The EMBO journal 33, 1227-42. PMID: 24797473

2. Moon, H. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 8541-6. PMID: 24853502

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-ICK Antibody (N451/29)

References

Datasheet

Anti-ICK Recombinant Antibody (N451/29).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ICK Recombinant Antibody (N451/29) (HV486023)

Overview

Images

References

Datasheet

SDS