

| Catalog No. | HD436014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-IVD Polyclonal Antibody (HD436014) is a rabbit polyclonal antibody detecting IVD in ELISA, IHC, WB. Suitable for Mouse, Rat, and Human.
Highlights
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| Species reactivity | Human, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human IVD (Ser46-His426). | ||||||||
| Target | Butyryl-CoA dehydrogenase, EC:1.3.8.1, EC:1.3.8.4, IVD, Isovaleryl-CoA dehydrogenase, mitochondrial | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P26440 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | P26440 | ||||||||
| Background | Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) is a ~46 kDa protein. A mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism, where isovaleryl-CoA (3-methylbutanoyl-CoA) is metabolized to 3-methylbut-2-enoyl-CoA. To a lesser extent, it also participates in the first step in fatty acid beta-oxidation, in which it catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexanoyl-CoA and butanoyl-CoA, using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor. 1. Mohsen, AW. et al. (1995) Biochemistry 34, 10146-52. PMID: 7640268 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-IVD polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
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