

| Catalog No. | HD436012 |
|---|---|
| Description |
Recombinant Human IVD Protein, N-His (HD436012) expressed in E. coli, spanning Ser46-His426. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P26440 |
| Protein length | Ser46-His426 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 44.02 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | Butyryl-CoA dehydrogenase, EC:1.3.8.1, EC:1.3.8.4, IVD, Isovaleryl-CoA dehydrogenase, mitochondrial |
| Background | Isovaleryl-CoA dehydrogenase, mitochondrial is a ~46 kDa protein. A mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism, where isovaleryl-CoA (3-methylbutanoyl-CoA) is metabolized to 3-methylbut-2-enoyl-CoA. To a lesser extent, it also participates in the first step in fatty acid beta-oxidation, in which it catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexanoyl-CoA and butanoyl-CoA, using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor. 1. Mohsen, AW. et al. (1995) Biochemistry 34, 10146-52. PMID: 7640268 |
| Note | For research use only |
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