Anti-Kir2.2 K+ channel Recombinant Antibody (N240/17) (HC427033)

Name: Anti-Kir2.2 K+ channel Recombinant Antibody (N240/17)
Brand: abinScience
SKU: HC427033
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC427033

Description

Anti-Kir2.2 K+ channel Recombinant Antibody (N240/17) (HC427033) is a mouse monoclonal antibody detecting KCNJ12/Kir2.2 K+ channel in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N240/17

Target

Inward rectifier K(+) channel Kir2.2v, IRK-2, Inward rectifier K(+) channel Kir2.2, Potassium channel, inwardly rectifying subfamily J member 12, IRK2, KCNJN1, KCNJ12, ATP-sensitive inward rectifier potassium channel 12

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-Kir2.2 K+ channel Antibody (N240/17) (abinScience Cat# HC427033, RRID:AB_3728394)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

ATP-sensitive inward rectifier potassium channel 12 (KCNJ12/Kir2.2 K+ channel) is a ~48 kDa protein. Inward rectifying potassium channel that probably participates in controlling the resting membrane potential in electrically excitable cells. It probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Kir2.2 K+ channel Antibody (N240/17)

References

Datasheet

Anti-Kir2.2 K+ channel Recombinant Antibody (N240/17).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Kir2.2 K+ channel Recombinant Antibody (N240/17) (HC427033)

Overview

Images

References

Datasheet

SDS