Anti-Human KLB/Beta-klotho Polyclonal Antibody (HV266014)

Name: Anti-Human KLB/Beta-klotho Polyclonal Antibody
Brand: abinScience
SKU: HV266014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV266014

Description

Anti-KLB Polyclonal Antibody (HV266014) is a rabbit polyclonal antibody detecting KLB in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KLB (Gly52-Phe508).

Target

Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL

Purification

Purified by antigen affinity column.

Accession

Q86Z14

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Beta-klotho (KLB) is a ~119 kDa protein. Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.

Note

For research use only.

Images

References

Datasheet