Anti-KCNA4/Kv1.4 Recombinant Antibody (L71/22) (HB186023)

Name: Anti-KCNA4/Kv1.4 Recombinant Antibody (L71/22)
Brand: abinScience
SKU: HB186023
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB186023

Description

Anti-Kv1.4 K+ channel Recombinant Antibody (L71/22) (HB186023) is a mouse monoclonal antibody detecting KCNA4/Kv1.4 K+ channel in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

L71/22

Target

Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, HPCN2, Voltage-gated K(+) channel HuKII, Potassium voltage-gated channel subfamily A member 4, KCNA4L, KCNA4, Voltage-gated potassium channel subunit Kv1.4

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-Kv1.4 K+ channel Antibody (L71/22) (abinScience Cat# HB186023, RRID:AB_3728161)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Potassium voltage-gated channel subfamily A member 4 (KCNA4/Kv1.4 K+ channel) is a ~73 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

1. Ramaswami, M. et al. (1990) Molecular and cellular neurosciences 1, 214-23. PMID: 19912772

2. Po, S. et al. (1993) Circulation research 72, 1326-36. PMID: 8495559

3. Imbrici, P. et al. (2006) The European journal of neuroscience 24, 3073-83. PMID: 17156368

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Kv1.4 K+ channel Antibody (L71/22)

References

Datasheet

Anti-KCNA4/Kv1.4 Recombinant Antibody (L71/22).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-KCNA4/Kv1.4 Recombinant Antibody (L71/22) (HB186023)

Overview

Images

References

Datasheet

SDS