

| Catalog No. | HB985013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25) (HB985013) is a mouse monoclonal antibody detecting KCNA5 in IHC, WB.
Highlights
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| Applications | IHC, WB | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | K7/25 | ||||
| Target | KCNA5, Voltage-gated potassium channel HK2, Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel subunit Kv1.5 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| RRID | Anti-Kv1.5 K+ channel Antibody (K7/25) (abinScience Cat# HB985013, RRID:AB_3728164) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Potassium voltage-gated channel subfamily A member 5 (KCNA5) is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. 1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714 2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Kv1.5 K+ channel Antibody (K7/25)
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