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Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25) (HB985013)

Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25)
Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25)
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Overview
Catalog No.HB985013
Description
Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25) (HB985013) is a mouse monoclonal antibody detecting KCNA5 in IHC, WB.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
ApplicationsIHC, WB
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a, kappa
Clone IDK7/25
Target KCNA5, Voltage-gated potassium channel HK2, Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel subunit Kv1.5
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
RRID

Anti-Kv1.5 K+ channel Antibody (K7/25) (abinScience Cat# HB985013, RRID:AB_3728164)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Potassium voltage-gated channel subfamily A member 5 (KCNA5) is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714
2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626
Note For research use only.
Images
  • Anti-Kv1.5 K+ channel Recombinant Antibody (K7/25)

    SDS-PAGE

    SDS-PAGE for Anti-Kv1.5 K+ channel Antibody (K7/25)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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