Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR-72) (VK669073)

Name: Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR-72)
Brand: abinScience
SKU: VK669073
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK669073

Description

Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR-72) (VK669073) is a human monoclonal antibody detecting MARV Glycoprotein GP,MARV Glycoprotein GP1 in ELISA, EM, Neutralization. Suitable for Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

Applications

ELISA, EM, Neutralization

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, lambda

Clone ID

MR-72

Target

Glycoprotein, GP1

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelope glycoprotein (GP1/Envelope glycoprotein 1) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection).

Note

For research use only.

Images

References

Datasheet

Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR-72).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-MARV Glycoprotein GP1 Recombinant Antibody (MR-72) (VK669073)

Overview

Images

References

Datasheet

SDS