

| Catalog No. | HA938023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Mitofusin-1 Recombinant Antibody (N111/27) (HA938023) is a mouse monoclonal antibody detecting MFN1 in IHC, WB.
Highlights
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| Applications | IHC, WB | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | N111/27 | ||||
| Target | Fzo homolog, Transmembrane GTPase MFN1, MFN1, Mitofusin-1 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| RRID | Anti-Mitofusin-1 Antibody (N111/27) (abinScience Cat# HA938023, RRID:AB_3728536) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Mitofusin-1 (MFN1) is a ~84 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). 1. Legros, F. et al. (2002) Molecular biology of the cell 13, 4343-54. PMID: 12475957 2. Santel, A. et al. (2003) Journal of cell science 116, 2763-74. PMID: 12759376 3. Qi, Y. et al. (2016) The Journal of cell biology 215, 621-629. PMID: 27920125 4. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Mitofusin-1 Antibody (N111/27)
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