Anti-Mitofusin-2 Recombinant Antibody (N153/3) (HF769013)

Name: Anti-Mitofusin-2 Recombinant Antibody (N153/3)
Brand: abinScience
SKU: HF769013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF769013

Description

Anti-Mitofusin-2 Recombinant Antibody (N153/3) (HF769013) is a mouse monoclonal antibody detecting MFN2 in IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Applications

IHC, WB

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

N153/3

Target

Transmembrane GTPase MFN2, Mitofusin-2, KIAA0214, CPRP1, MFN2

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

RRID

Anti-Mitofusin-2 Antibody (N153/3) (abinScience Cat# HF769013, RRID:AB_3728067)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Mitofusin-2 (MFN2) is a ~86 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes.

1. Santel, A. et al. (2001) Journal of cell science 114, 867-74. PMID: 11181170

2. Rojo, M. et al. (2002) Journal of cell science 115, 1663-74. PMID: 11950885

3. Casasnovas, C. et al. (2010) Journal of medical genetics 47, 249-56. PMID: 19889647

4. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

5. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303

6. Chen, Y. et al. (2013) Science (New York, N.Y.) 340, 471-5. PMID: 23620051

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mitofusin-2 Antibody (N153/3)

References

Datasheet

Anti-Mitofusin-2 Recombinant Antibody (N153/3).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mitofusin-2 Recombinant Antibody (N153/3) (HF769013)

Overview

Images

References

Datasheet

SDS