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Anti-Mouse CD11b/ITGAM Recombinant Antibody (DC13), PE (MY474127)

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Overview

Catalog No.	MY474127
Description	Anti-Mouse CD11b/ITGAM Antibody (DC13), PE [DC13] (MY474127) is a rat monoclonal antibody detecting CD11b in FCM, IF. Suitable for Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	FCM, IF
Host species	Rat
Isotype	VHH-rFc (IgG2b)
Clone ID	DC13
Conjugation	PE
Clonality	Monoclonal
Target	Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam
Endotoxin level	Please contact with the lab for this information.
Accession	P05555
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain. 1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD11b/ITGAM Recombinant Antibody (DC13), PE.pdf

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Anti-Mouse CD11b/ITGAM Recombinant Antibody (DC13), PE