Anti-Mouse CD124/IL4RA Antibody (REGN1103) (MB732013)

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Overview

Catalog No.	MB732013
Description	Anti-Mouse CD124/IL4RA Antibody (REGN1103） [REGN1103] (MB732013) is a mouse monoclonal antibody detecting CD124/IL4RA in Neutralization. Suitable for Mouse.
Species reactivity	Mouse
Applications	Neutralization
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	REGN1103
Clonality	Monoclonal
Target	CD124/IL4RA
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P16382
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble interleukin-4 receptor subunit alpha, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP, Il4r
Background	Interleukin-4 receptor subunit alpha (CD124/IL4RA) is a ~87 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Note	For research use only.