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Anti-Mouse Aminopeptidase N/CD13 Polyclonal Antibody (MB650014)

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Overview
Catalog No.MB650014
Description
Anti-Mouse CD13/ANPEP Polyclonal Antibody (MB650014) is a rabbit polyclonal antibody detecting Anpep. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse CD13/ANPEP (Thr79-Glu285).
Target AP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Anpep, CD13, EC:3.4.11.2, Lap-1, Lap1, Membrane protein p161, Microsomal aminopeptidase, mAPN
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P97449
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Aminopeptidase N (CD13/ANPEP) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity.

1. Larsen, SL. et al. (1996) The Journal of experimental medicine 184, 183-9. PMID: 8691132
2. Fairweather, SJ. et al. (2012) The Biochemical journal 446, 135-48. PMID: 22677001
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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